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Rev. mex. cardiol ; 26(1): 39-52, ene.-mar. 2015. ilus, tab
Article in Spanish | LILACS-Express | LILACS | ID: lil-747770

ABSTRACT

La disfunción cardiaca y la renal coexisten con alta prevalencia. Se ha definido a esta entidad clínica como síndrome cardiorrenal y una de sus características principales es la resistencia al tratamiento. Se han descrito múltiples hipótesis para explicar su fisiopatología, como la desregulación hemodinámica y, recientemente, mecanismos neurohumorales e inmunológicos que intervienen en su desarrollo y perpetuación. Se clasifica de acuerdo con su forma de presentación y componentes fisiopatológicos. Existen distintos enfoques terapéuticos para controlar o limitar el progreso de la enfermedad. Esta revisión discute y analiza la información actual sobre la fisiopatología, la clasificación y el tratamiento de esta entidad.


There is a high prevalence of heart failure associated to kidney failure or viceversa. This association has been defined as a clinical entity: cardiorenal syndrome and one of its main characteristics is the resistance to treatment. Multiple hypotheses have been proposed to explain the pathophysiology of this syndrome, such as hemodynamic deregulation and recently, other neurohormonal and immunological mechanisms involved in the development and perpetuation of this pathology. Classifications have been based on the form of presentation or physiopathological manifestations. Different therapeutic approaches have been proposed to control or limit the progress of this disease. This review discusses and analyzes the current information on pathophysiology, different classifications and treatment.

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